Effects of Ecological Rythmic-acoustic Stimulation (E-RAS) on Motor Skills in Individuals With Parkinson's Disease

Effects of Ecological Rythmic-acoustic Stimulation (E-RAS) on Motor Skills in Individuals

Patrocinadores

Patrocinador principal: University of Cagliari

Fuente University of Cagliari
Resumen breve

The use of rhythmic auditory stimulation (RAS) has been proven useful in the management of gait disturbances induced by Parkinson's disease (PD). Typically, the stimuli used to provide RAS consist of metronome or music-based sounds, which are not related with the auditory experience of walking. Based on previous laboratory research, it is hypothesized that the use of ecological sounds deriving from biological motion (i.e., footstep sounds) could have a greater impact compared to artificial sounds (i.e., metronome sounds), within a rehabilitation program. In a double-blind experiment, it was investigated the effects of 5 weeks of supervised rehabilitation integrated with RAS. Thirty-two individuals affected by PD (age 68.2 ± 10.5, Hoehn and Yahr 1,5-3) were randomly assigned to one of the two conditions (artificial vs. ecological sounds). Spatio-temporal parameters of gait and clinical variables were assessed before the rehabilitation period, at its end, and after a 3-month follow-up. The results revealed that the rehabilitation program integrated with RAS had positive effects on the majority of objective and subjective measures, independently of the type of sound. However, when the two groups were examined separately, the patients assigned to the ecological RAS condition were the only who improved both in terms of cadence and gait speed. Overall, the hypothesized greater effect of the ecological sounds compared to artificial sounds was only partially supported by data.

Estado general Completed
Fecha de inicio November 1, 2014
Fecha de Terminación July 1, 2017
Fecha de finalización primaria December 31, 2016
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
Walking speed 5 weeks
Resultado secundario
Medida Periodo de tiempo
Hip Flexion-extension 5 weeks
Knee Flexion-extension 5 weeks
Ankle Dorsi- Plantar-flexion 5 weeks
GPS 5 weeks
Inscripción 32
Condición
Intervención

Tipo de intervención: Other

Nombre de intervención: Administration of rhytmic acoustic stimuli for gait training

Descripción: The intervention consist in 5 weeks, 20 min/day gait training assisted by rhythmic acoustic stimuli administered using a portable MP3 player

Elegibilidad

Criterios:

Inclusion Criteria:

- diagnosis of PD according to the UK Brain Bank criteria;

- ability to walk independently;

- absence of relevant hearing impairments which could prevent the correct perception of the auditory cues;

- absence of significant cognitive impairment (i.e., Mini-Mental Status Examination (MMSE) > 24; Frontal Assessment Battery (FAB) > 13);

- absence of psychiatric or severe systemic illnesses;

- mild-to-moderate disability assessed by means of the modified Hoehn and Yahr (H&Y) staging scale (1,5 ≤ H&Y ≤ 3);

- no engagement in any rehabilitative program in the 3 months before the beginning of the study

Exclusion Criteria:

-

Género: All

Edad mínima: 50 Years

Edad máxima: 90 Years

Voluntarios Saludables: Accepts Healthy Volunteers

Ubicación
Instalaciones: General Hospital "G. Brotzu"
Ubicacion Paises

Italy

Fecha de verificación

July 2017

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: University of Cagliari

Nombre completo del investigador: Massimiliano Pau

Título del investigador: Associate Professor

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Número de brazos 2
Grupo de brazo

Etiqueta: Artificial Sounds

Tipo: Experimental

Descripción: Participants were provided headphones and a portable MP3 device which played a metronome tick at specified rhythm calculated as follows: a) if a patient's cadence was below the normality, the BPM of the stimulus was set at a value of 10% higher than one's own cadence; b) if a patient's cadence was below, but close to normality (less than 10% difference), the BPM of the stimulus was set at normality values; c) if a patient's cadence was above the normality, the BPM of the stimulus was set at a value equal to one's own cadence. Participants performed daily 30 minutes of walking assisted by the rhythmic acoustic stimuli.

Etiqueta: Ecological Sounds

Tipo: Experimental

Descripción: Participants were provided headphones and a portable MP3 device which played an ecological rhythmic sound obtained by actual footsteps of human at specified rhythm calculated as follows: a) if a patient's cadence was below the normality, the BPM of the stimulus was set at a value of 10% higher than one's own cadence; b) if a patient's cadence was below, but close to normality (less than 10% difference), the BPM of the stimulus was set at normality values; c) if a patient's cadence was above the normality, the BPM of the stimulus was set at a value equal to one's own cadence. Participants performed daily 30 minutes of walking assisted by the rhythmic acoustic stimuli.

Datos del paciente No
Información de diseño del estudio

Asignación: Randomized

Modelo de intervención: Parallel Assignment

Descripción del modelo de intervención: Participants were randomly assigned to one of the two groups (artificial or ecological RAS) and were evaluated in three moments: before the rehabilitative treatment (T0), at the end of the 5 week rehabilitative treatment (T5), and 3 months after the end of the treatment, namely 17 weeks after the first assessment (T17).

Propósito primario: Treatment

Enmascaramiento: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Fuente: ClinicalTrials.gov