Cognitive Rehab for Parkinson's

Cognitive Rehabilitation for Veterans With Parkinson's Disease

Patrocinadores

Patrocinador principal: VA Office of Research and Development

Fuente VA Office of Research and Development
Resumen breve

This study will examine the feasibility of an at-home cognitive training program that incorporates both memory training and online computerized cognitive training (CCT) software. Data will also be collected to determine if this program improves thinking and memory as well as everyday function. The hypothesis is that memory and cognitive training combined , compared to memory training alone or will lead to greater improvements in cognitive performance and daily function.

Descripción detallada

The objective of this study is to examine feasibility of an at-home cognitive rehabilitation program that incorporates both prospective implementation intentions strategies (PRIIS) and an existing web-based executive function (EF) computerized cognitive training (CCT) software for Veterans with Parkinson's disease (PD) and to collect pilot data to determine the impact of this program on cognition and everyday function. The central hypothesis is that CCT+PRIIS, compared to CCT alone and an active control group, will lead to greater improvements in cognitive performance and daily function. This innovative study uses a set of on-line training games that target aspects of EF susceptible in PD and trains the transfer of cognitive benefits to everyday function, using PRIIS, for Veterans with PD and mild cognitive impairment in executive function. Additionally, training is conducted at home allowing for convenience and flexibility for participants.

Estado general Recruiting
Fecha de inicio January 27, 2020
Fecha de Terminación October 3, 2022
Fecha de finalización primaria October 1, 2021
Fase N/A
Tipo de estudio Interventional
Resultado primario
Medida Periodo de tiempo
change in NIH sponsored Executive Abilities: Measures and Instruments for neurobehavioral evaluation and re-search (NIH-EXAMINER) executive composite score week 0 (before intervention begins), 8 weeks, 12 weeks
Inscripción 45
Condición
Intervención

Tipo de intervención: Behavioral

Nombre de intervención: cognitive training

Descripción: Cognitive training consists of a set of computerize games played on an iPad at home. Training will include 4 sessions/week for 8 weeks. Each session will take 30min. Total hours of training is 16 hours.

Tipo de intervención: Behavioral

Nombre de intervención: active control cognitive training

Descripción: The active control consists of a set of computerized games played on an iPad. Training will include 4 sessions/week for 8 weeks. Each session will take 30min. Total hours of training is 16 hours.

Etiqueta de grupo de brazo: active control for cognitive and memory strategy training

Tipo de intervención: Behavioral

Nombre de intervención: memory strategy training

Descripción: the participant's prospective memory strategies will be developed with researchers. Participants will be engage in the strategies daily; this will take only a few minutes a day to accomplish.

Etiqueta de grupo de brazo: cognitive and memory strategy training

Tipo de intervención: Behavioral

Nombre de intervención: memory strategy training

Descripción: the participant's prospective memory strategies will be developed with researchers. Participants will be engage in the strategies daily; this will take only a few minutes a day to accomplish.

Elegibilidad

Criterios:

Inclusion Criteria:

- Veterans who seek services at Hines VA Hospital

- Diagnosis of PD as determined by the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria

- Meet criteria for having mild cognitive impairment

- Receiving stable (i.e., no changes in medication and medication dose) medication and who are expected to remain on stable medication for the duration of the RCT

- 50 years or older

- Speak and read English

Exclusion Criteria:

- Dementia

- Failure to demonstrate decision making capacity

- Cholinesterase inhibitor medication

- History of deep brain stimulation surgery

- Severe depression

- Severe anxiety

- Severe apathy

Género: All

Edad mínima: 50 Years

Edad máxima: N/A

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
Sandra L. Kletzel, PhD BA Principal Investigator Edward Hines Jr. VA Hospital, Hines, IL
Contacto general

Apellido: Sandra L Kletzel, PhD BA

Teléfono: (708) 202-5735

Email: [email protected]

Ubicación
Instalaciones: Estado: Contacto: Copia de seguridad de contactos: Investigador: Edward Hines Jr. VA Hospital, Hines, IL William Wolf, PhD 708-202-5689 [email protected] Sandra L. Kletzel, PhD BA Principal Investigator
Ubicacion Paises

United States

Fecha de verificación

August 2020

Fiesta responsable

Tipo: Sponsor

Palabras clave
Tiene acceso ampliado No
Condición Examinar
Número de brazos 3
Grupo de brazo

Etiqueta: cognitive and memory strategy training

Tipo: Experimental

Descripción: The cognitive training will include 4 sessions/week for 8 weeks. Each session will take 30min. Total hours of training is 16 hours. For memory strategy training, strategies will be performed daily; this will take only a few minutes a day to accomplish.

Etiqueta: cognitive and memory strategy control training

Tipo: Active Comparator

Descripción: The cognitive training will include 4 sessions/week for 8 weeks. Each session will take 30min. Total hours of training is 16 hours. For the active control of memory strategy training, strategies will be performed daily; this will take only a few minutes a day to accomplish.

Etiqueta: active control for cognitive and memory strategy training

Tipo: Active Comparator

Descripción: The cognitive training will include 4 sessions/week for 8 weeks. Each session will take 30min. Total hours of training is 16 hours. For the active control of memory strategy training, strategies will be performed daily; this will take only a few minutes a day to accomplish.

Datos del paciente Yes
Información de diseño del estudio

Asignación: Randomized

Modelo de intervención: Parallel Assignment

Descripción del modelo de intervención: randomized control trial. three arms to the study

Propósito primario: Treatment

Enmascaramiento: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Fuente: ClinicalTrials.gov