Artificial Intelligence to Assess the Association Between Facial Characteristics and Coronary Artery Diseases
연구 개요
상세 설명
Several age-related appearance factors were described associated with increased risk of coronary artery diseases (CAD). However, several limitations made these facial risk factors hard to be utilized in clinical practice, including 1) low prevalence in CAD patients, 2) lack of specific definition, 3) poor reproducibility in artificial recognition.
Thus, the investigators designed a multi-center, cross-sectional study to explore the association between facial characteristics and CAD and evaluate the diagnostic efficacy of appearance factors for CAD. The investigators will recruit patients undergoing coronary angiography or coronary computer tomography angiography. Patients' baseline information and facial images will be collected. First, the investigators will explore the facial factors associated with CAD by using artificial intelligence technology to compare facial photographs between patients with CAD and without CAD. Secondary, the investigators will evaluate the dose-response relationship between facial characteristics and CAD. Third, the investigators will establish a CAD risk model based on facial factors, and evaluate the diagnostic effect of the model.
연구 유형
등록 (실제)
연락처 및 위치
연구 장소
-
-
Beijing
-
Beijing, Beijing, 중국, 100032
- Fuwai Hospital
-
Beijing, Beijing, 중국, 100032
- Beijing Anzhen Hospital
-
Beijing, Beijing, 중국, 100032
- Guanganmen Hospital, Chinese Academy of Traditional Chinese Medicine
-
-
Hubei
-
Wuhan, Hubei, 중국, 430000
- Wuhan Union Hospital
-
-
Jiangsu
-
Xuzhou, Jiangsu, 중국, 221000
- Xuzhou Third People's Hospital
-
-
Liangning
-
Dalian, Liangning, 중국, 116000
- The First Affiliated Hospital of Dalian Medical University
-
-
Shanghai
-
Shanghai, Shanghai, 중국, 200000
- Shanghai East Hospital
-
Shanghai, Shanghai, 중국, 200000
- Shanghai Renji Hospital
-
-
Zhejiang
-
Wenzhou, Zhejiang, 중국, 325000
- The fisrt affiliated hospital of Wenzhou medical university
-
-
참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
샘플링 방법
연구 인구
설명
Inclusion Criteria:
- Undergoing coronary angiography or coronary computer tomography angiography
- Written informed consent
Exclusion Criteria:
- Prior percutaneous coronary intervention (PCI)
- Prior coronary artery bypass graft (CABG)
- Screening coronary artery disease before treating other heart diseases
- Without blood biochemistry outcome
- With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
- Other situations which make patients fail to be photographed
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
코호트 및 개입
그룹/코호트 |
개입 / 치료 |
|---|---|
|
Model establishment and test group
Patients undergoing coronary angiography or coronary computer tomography angiography will be enrolled.
Patients data will be used to establish the facial based diagnostic model of coronary artery diseases, and to prospectively validate the diagnostic effectiveness of the model.
|
개입 없음
|
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Sensitivity of diagnostic model
기간: at the end of enrollment (6 months)
|
The sensitivity of coronary artery diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Specificity of diagnostic model
기간: at the end of enrollment (6 months)
|
The specificity of coronary artery diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
|
Specificity of diagnostic model
기간: at the end of enrollment (6 months)
|
Area under receiver operating curve (AUC) of diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
|
Positive predictive value (PPV)
기간: at the end of enrollment (6 months)
|
PPV of diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
|
Negative predictive value (NPV)
기간: at the end of enrollment (6 months)
|
NPV of diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
|
Diagnostic accuracy rate
기간: at the end of enrollment (6 months)
|
Diagnostic accuracy rate of diagnostic model assessed in model test group
|
at the end of enrollment (6 months)
|
공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .
관상동맥 질환에 대한 임상 시험
-
Chinese Academy of Medical Sciences, Fuwai HospitalMedtronic; CCRF Consulting Co., Ltd.빼는Transradial-transfemoral Coronary Interventions 비교
-
CCRF Consulting Co., Ltd.Peking University First Hospital; Terumo Medical(shanghai) Co.,Ltd.알려지지 않은심장 또는 뇌혈관 질환 무료 요금 | Transradial-transfemoral Coronary Interventions 비교중국
-
Hospital Clinic of BarcelonaAstraZeneca완전한CTO(Chronic Total Occlusion)를 위한 PCI(Percutaneous Coronary Intervention)를 받을 예정인 환자스페인
-
Micell TechnologiesCardialysis BV; ClinLogix. LLC알려지지 않은
-
University Medical Center Groningen모병
-
University of PittsburghNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); US Department...완전한신장 질환 | 만성 신장 질환 | 급성 신부전 | 관상동맥(Artery); 질병
개입 없음에 대한 임상 시험
-
Otsuka Pharmaceutical Factory, Inc.Celerion완전한
-
Medical Center HaaglandenLeiden University Medical Center알려지지 않은
-
Medical Center HaaglandenLeiden University Medical Center알려지지 않은