Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[SponsorSearch] ( National Institute of Neurological Disorders and Stroke AND NINDS )
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NCTID/Status
Study
Last Changed
651
NCT01730443
Terminated
Terminated
Blood Biomarkers of Injury and Outcome in Traumatic Brain Injury
Conditions: Traumatic Brain Injury
Conditions: Traumatic Brain Injury
December 2, 2014
652
NCT01705327
Completed
Completed
Fox Investigation for New Discovery of Biomarkers
Conditions: Parkinson's Disease
Conditions: Parkinson's Disease
October 2, 2015
653
NCT01694953
Recruiting
Recruiting
The Natural History Study of Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)
Conditions: Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)
Conditions: Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)
February 26, 2019
654
NCT01694940
Recruiting
Recruiting
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Conditions: Mitochondrial Disorders; Mitochondrial Genetic Disorders; Mitochondrial Diseases; Disorder of Mitochondrial Respiratory Chain Complexes; Deletion and Duplication of Mitochondrial DNA
Conditions: Mitochondrial Disorders; Mitochondrial Genetic Disorders; Mitochondrial Diseases; Disorder of Mitochondrial Respiratory Chain Complexes; Deletion and Duplication of Mitochondrial DNA
August 1, 2019
655
NCT01660672
Completed
Completed
Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria
Conditions: Seizure; Epilepsy; Cerebral Malaria
Intervention: LEVETIRACETAM
Conditions: Seizure; Epilepsy; Cerebral Malaria
Intervention: LEVETIRACETAM
August 3, 2016
656
NCT01659541
Recruiting
Recruiting
Stimulation With Wire Leads to Restore Cough
Conditions: Spinal Cord Injuries; Spinal Cord Diseases; Paralysis; Central Nervous System Diseases; Cough; Trauma, Nervous System; Wounds and Injuries
Intervention: Expiratory Muscle Stimulator, Implantation Of Device
Conditions: Spinal Cord Injuries; Spinal Cord Diseases; Paralysis; Central Nervous System Diseases; Cough; Trauma, Nervous System; Wounds and Injuries
Intervention: Expiratory Muscle Stimulator, Implantation Of Device
June 28, 2019
657
NCT01651884
Completed
Completed
Effects of tDCS Versus HD-tDCS for Stroke Rehabilitation
Conditions: Chronic Aphasia
Intervention: HD-tDCS (Soterix), Transcranial Direct Current Stimulation (Neuroconn)
Conditions: Chronic Aphasia
Intervention: HD-tDCS (Soterix), Transcranial Direct Current Stimulation (Neuroconn)
August 25, 2015
658
NCT01650636
Completed
Completed
Patient-Partner Stress Management Effects on Chronic Fatigue Syndrome Symptoms and Neuroimmune Process
Conditions: Chronic Fatigue Syndrome
Intervention: Patient-Partner Videotelephone-delivered Health Information (PP-T-HI), Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management Intervention (PP-T-CBSM)
Conditions: Chronic Fatigue Syndrome
Intervention: Patient-Partner Videotelephone-delivered Health Information (PP-T-HI), Patient-Partner Videotelephone-delivered Cognitive Behavioral Stress Management Intervention (PP-T-CBSM)
December 6, 2018
659
NCT01581281
Terminated
Terminated
The Childhood and Adolescent Migraine Prevention Study
Conditions: Migraine; Migraine Disorders; Headache
Intervention: Amitriptyline, Topiramate, Placebo
Conditions: Migraine; Migraine Disorders; Headache
Intervention: Amitriptyline, Topiramate, Placebo
July 11, 2017
660
NCT01565551
Completed
Completed
Transforming Research and Clinical Knowledge in TBI Pilot
Conditions: Traumatic Brain Injury
Intervention: N/A (Observational Study)
Conditions: Traumatic Brain Injury
Intervention: N/A (Observational Study)
January 3, 2014
661
NCT01556230
Recruiting
Recruiting
Prospective Study of Clinically Nonfunctioning Pituitary Adenomas
Conditions: Pituitary Adenoma; Pituitary Tumor
Intervention: Surgical Intervention For CNFA, Radiotherapy For CNFA
Conditions: Pituitary Adenoma; Pituitary Tumor
Intervention: Surgical Intervention For CNFA, Radiotherapy For CNFA
February 16, 2019
662
NCT01521130
Completed
Completed
Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children
Conditions: Benign Childhood Epilepsy With Centro-Temporal Spikes
Intervention: Levetiracetam
Conditions: Benign Childhood Epilepsy With Centro-Temporal Spikes
Intervention: Levetiracetam
November 9, 2017
663
NCT01506518
Active, not recruiting
Active, not recruiting
Double Push Acoustic Radiation Force (DP ARF) Ultrasound for Monitoring Degeneration in Duchenne Muscular Dystrophy
Conditions: Muscular Dystrophy, Duchenne
Conditions: Muscular Dystrophy, Duchenne
May 3, 2019
664
NCT01499173
Completed
Completed
A Community Partnership to Treat Stroke
Conditions: Stroke
Intervention: Stroke Preparedness Intervention
Conditions: Stroke
Intervention: Stroke Preparedness Intervention
August 4, 2017
665
NCT01497886
Active, not recruiting
Active, not recruiting
Effect of Intervention to Improve Stroke Recognition
Conditions: Stroke
Intervention: Hip Hop Stroke Educational Program, Nutrition Education Program
Conditions: Stroke
Intervention: Hip Hop Stroke Educational Program, Nutrition Education Program
January 25, 2018
666
NCT01480349
Completed
Completed
Shunt Outcomes of Post-Hemorrhagic Hydrocephalus
Conditions: Post-Hemorrhagic Hydrocephalus
Conditions: Post-Hemorrhagic Hydrocephalus
December 21, 2017
667
NCT01435798
Completed
Completed
Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical Trial
Conditions: Central Neuropathic Pain; Allodynia; Spinal Cord Injury
Intervention: Dextromethorphan
Conditions: Central Neuropathic Pain; Allodynia; Spinal Cord Injury
Intervention: Dextromethorphan
February 15, 2017
668
NCT01378273
Active, not recruiting
Active, not recruiting
Preterm Erythropoietin Neuroprotection Trial (PENUT Trial)
Conditions: Extreme Prematurity
Intervention: Epo, Control
Conditions: Extreme Prematurity
Intervention: Epo, Control
October 9, 2019
669
NCT01373840
Completed
Completed
Role of Dopamine Receptors in Primary Focal Dystonias
Conditions: Healthy; Focal Dystonias
Conditions: Healthy; Focal Dystonias
May 9, 2018
670
NCT01340885
Unknown status
Unknown status
Cognitive Decline in Non-demented PD
Conditions: Parkinson's Disease
Intervention: Strattera, Exelon, Placebo
Conditions: Parkinson's Disease
Intervention: Strattera, Exelon, Placebo
November 9, 2012
671
NCT01316666
Completed
Completed
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension; Pure Autonomic Failure; Multiple System Atrophy; Parkinson's Disease
Conditions: Orthostatic Hypotension; Pure Autonomic Failure; Multiple System Atrophy; Parkinson's Disease
January 4, 2017
672
NCT01268280
Terminated
Terminated
Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis
Conditions: Myasthenia Gravis
Intervention: Placebo, 250 Mg CK-2017357, 500 Mg CK-2017357
Conditions: Myasthenia Gravis
Intervention: Placebo, 250 Mg CK-2017357, 500 Mg CK-2017357
September 18, 2019
673
NCT01226654
Terminated
Terminated
Quantitative Imaging and Proton Spectroscopy in Multiple Sclerosis
Conditions: Multiple Sclerosis
Intervention: Magnetic Resonance Imaging
Conditions: Multiple Sclerosis
Intervention: Magnetic Resonance Imaging
July 28, 2017
674
NCT01220739
Terminated
Terminated
Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery
Conditions: Ischemic Stroke
Intervention: Transcranial Laser Therapy
Conditions: Ischemic Stroke
Intervention: Transcranial Laser Therapy
October 7, 2016
675
NCT01197196
Unknown status
Unknown status
Behavioral Weight Loss as a Treatment for Migraine in Obese Women
Conditions: Migraine; Obesity
Intervention: Behavioral Weight Loss Intervention, Migraine Education
Conditions: Migraine; Obesity
Intervention: Behavioral Weight Loss Intervention, Migraine Education
December 20, 2016
676
NCT01169181
Unknown status
Unknown status
AMES + Brain Stimulation
Conditions: Stroke; Cerebrovascular Accident; Plegia
Intervention: AMES + Brain Stimulation
Conditions: Stroke; Cerebrovascular Accident; Plegia
Intervention: AMES + Brain Stimulation
December 7, 2016
677
NCT01167608
Completed
Completed
Barriers to Mental Healthcare Utilization in Parkinson's Disease
Conditions: Parkinson's Disease; Depression; Anxiety
Intervention: No Intervention. This Is A Cross-sectional Survey Study.
Conditions: Parkinson's Disease; Depression; Anxiety
Intervention: No Intervention. This Is A Cross-sectional Survey Study.
June 26, 2019
678
NCT01162226
Completed
Completed
Computer-Based Balance Training for People With Parkinson's Disease
Conditions: Parkinson's Disease
Intervention: Gait And Balance Training Program
Conditions: Parkinson's Disease
Intervention: Gait And Balance Training Program
April 17, 2012
679
NCT01158807
Recruiting
Recruiting
Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
Conditions: Hereditary Hemorrhagic Telangiectasia
Conditions: Hereditary Hemorrhagic Telangiectasia
October 30, 2019
680
NCT01152944
Terminated
Terminated
Mechanisms of Stroke in Intracranial Stenosis
Conditions: Stroke
Conditions: Stroke
February 6, 2012
681
NCT01124461
Completed
Completed
BIRN (Biomedical Informatics Research Network) Resources Facilitate the Personalization of Malignant Brain Tumor
Conditions: GLIOBLASTOMA MULTIFORME; Brain Neoplasm
Conditions: GLIOBLASTOMA MULTIFORME; Brain Neoplasm
May 3, 2018
682
NCT01115270
Completed
Completed
A Study Comparing Shunt Placement Versus Endoscopic Third Ventriculostomy in the Treatment of Hydrocephalus
Conditions: Hydrocephalus, Normal Pressure
Intervention: Non-invasive Measures
Conditions: Hydrocephalus, Normal Pressure
Intervention: Non-invasive Measures
May 6, 2016
683
NCT01113684
Completed
Completed
Study of Subthalamic Brain Stimulation in Parkinson Disease (PD)
Conditions: Parkinson Disease
Intervention: Implantable Pulse Generator (deep Brain Stimulator)
Conditions: Parkinson Disease
Intervention: Implantable Pulse Generator (deep Brain Stimulator)
May 9, 2018
684
NCT01108965
Completed
Completed
Study of Shunt Flow Sensor Accuracy in Extra-ventricular Drains.
Conditions: Hydrocephalus; Nervous System Diseases; Infant, Newborn Diseases
Conditions: Hydrocephalus; Nervous System Diseases; Infant, Newborn Diseases
May 25, 2016
685
NCT01071408
Completed
Completed
Trial of a Secondary Stroke Prevention Program
Conditions: Ischemic Stroke; Transient Ischemic Attack
Intervention: Stroke Prevention Care Program
Conditions: Ischemic Stroke; Transient Ischemic Attack
Intervention: Stroke Prevention Care Program
May 14, 2012
686
NCT01068522
Unknown status
Unknown status
Study to Improve Outcomes for Survivors of Traumatic Brain Injury in Latin America
Conditions: Traumatic Brain Injury; Brain Injuries
Intervention: Parenchymal Intracranial Pressure Monitor, Treatment Based On Clinical And Imaging Observations
Conditions: Traumatic Brain Injury; Brain Injuries
Intervention: Parenchymal Intracranial Pressure Monitor, Treatment Based On Clinical And Imaging Observations
October 31, 2012
687
NCT01022073
Completed
Completed
Follow Up Study for Treatment of Parkinson's Disease With Deep Brain Stimulation
Conditions: Parkinson Disease
Conditions: Parkinson Disease
May 4, 2016
688
NCT01009866
Terminated
Terminated
March 18, 2015
689
NCT01007786
Completed
Completed
The Ventricular Catheter Placement Study: Assessment of Efficacy and Safety of an Ultrasound Guided Shunt Insertion Technique
Conditions: Pediatric Hydrocephalus
Conditions: Pediatric Hydrocephalus
June 12, 2012
690
NCT00995215
Completed
Completed
Sub-study to Spinal Cord Stimulation to Restore Cough
Conditions: Spinal Cord Injuries; Spinal Cord Diseases; Paralysis; Central Nervous System Diseases; Cough
Intervention: Spinal Cord Stimulation, Expiratory Muscle Stimulator
Conditions: Spinal Cord Injuries; Spinal Cord Diseases; Paralysis; Central Nervous System Diseases; Cough
Intervention: Spinal Cord Stimulation, Expiratory Muscle Stimulator
January 30, 2018
691
NCT00983723
Unknown status
Unknown status
Clinical Proteomic Research for the Brain
Conditions: Ischemic Brain Injury; Stroke; Healthy Individual; Patent Foramen Ovale (PFO); Neurovascular Injury
Conditions: Ischemic Brain Injury; Stroke; Healthy Individual; Patent Foramen Ovale (PFO); Neurovascular Injury
May 22, 2013
692
NCT00968227
Completed
Completed
Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage
Conditions: Subarachnoid Hemorrhage; Vasospasm
Intervention: Red Blood Cell Transfusion
Conditions: Subarachnoid Hemorrhage; Vasospasm
Intervention: Red Blood Cell Transfusion
March 5, 2017
693
NCT00611481
Completed
Completed
Study of Tai Chi Exercise and Balance in Persons With Parkinson's Disease
Conditions: Parkinson's Disease
Intervention: Tai Chi, Strength Training, Low-Impact Exercise Control
Conditions: Parkinson's Disease
Intervention: Tai Chi, Strength Training, Low-Impact Exercise Control
October 10, 2011
694
NCT00930280
Active, not recruiting
Active, not recruiting
Genetic and Environmental Risk Factors for Hemorrhagic Stroke-GERFHS III
Conditions: Stroke
Conditions: Stroke
September 25, 2019
695
NCT00920699
Completed
Completed
Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)
Conditions: Huntington's Disease
Intervention: CoQ10
Conditions: Huntington's Disease
Intervention: CoQ10
August 25, 2017
696
NCT00894803
Completed
Completed
Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke
Conditions: Ischemic Stroke; Stroke; Brain Infarction
Intervention: Eptifibatide, Rt-PA
Conditions: Ischemic Stroke; Stroke; Brain Infarction
Intervention: Eptifibatide, Rt-PA
March 26, 2014
697
NCT00873509
Completed
Completed
Buspirone in the Treatment of 2-6 Year Old Children With Autistic Disorder
Conditions: Autistic Disorder
Intervention: Buspirone, Buspirone, Placebo
Conditions: Autistic Disorder
Intervention: Buspirone, Buspirone, Placebo
July 25, 2016
698
NCT00873015
Completed
Completed
Safety and Pharmacokinetic Evaluation of Nitrite for Prevention of Cerebral Vasospasm
Conditions: Subarachnoid Hemorrhage
Intervention: Sodium Nitrite, Saline
Conditions: Subarachnoid Hemorrhage
Intervention: Sodium Nitrite, Saline
May 9, 2017
699
NCT00870779
Completed
Completed
Fluorescence Guided Resection of Brain Tumors
Conditions: Brain Tumors
Intervention: 5-aminolevulinic Acid
Conditions: Brain Tumors
Intervention: 5-aminolevulinic Acid
June 12, 2019
700
NCT00844129
Completed
Completed
Spinal Abnormalities in Neurofibromatosis Type 1 (NF1)
Conditions: Neurofibromatosis Type 1
Conditions: Neurofibromatosis Type 1
April 30, 2018
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.